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Mass Spectrometry Analysis

Mass spectrometry (MS) is a valuable technique for identifying and quantifying analytes based on their masses. Mass spectrometry can be coupled with various instruments to separate analytes from complex matrices. Some of the techniques available here at Impact Analytical include the following:

Gas Chromatography-MS (GC-MS)

We have the capabilities to analyze samples using either headspace sampling, for volatile analytes, or liquid injection sampling, for semi-volatile analytes. GC-MS is good for analyzing small organic molecules, and our access to an extensive library of materials means that each component can be identified accurately.

Liquid Chromatography-MS (LC-MS)

LC-MS is a powerful tool, and is good for a large range of organic analytes, including those that may be too large or nonvolatile to analyze by GC-MS. This technique can be used for chemical structure confirmation, identification of unknowns, and more.  Our state-of-the-art instruments include UPLC separation systems with Accurate Mass Q-TOF, versatile enough for both identification and quantitative analyses. Our in-house databases have hundreds of compounds, including polymer additives, pharmaceutical impurities, surfactants, degradation products, and color bodies. We offer both electrospray (ESI) and atmospheric pressure chemical ionization (APCI) modes.

Inductively coupled plasma (ICP-MS) 

An elemental analysis, this technique is used to measure inorganic materials.

Whether your project is the deformation of a competitive product, extractables/leachables for pharmaceutical packaging, or confirmation of components in a mixture, mass spectrometry is a must. Impact Analytical has the expertise to analyze your materials, and provide you with data you can be confident in.  All equipment is qualified for testing under cGMP and GLP  (ISO 9001:2015, FDA, EPA) guidelines, so that you  can trust your results. 

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