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Qualitative and Quantitative Analysis of Phthalate Compounds

Phthalates are routinely added to polymeric materials to serve as plasticizers, thereby improving the mechanical properties of the material. They are a softening and flexibility-inducing group of chemical esters, and their levels are of ongoing concern, due to their wide usage in our everyday products such as cups and bowls, kitchen equipment, car parts, seats, food wrappers and packaging of cosmetics, with personal care items containing phthalates including perfume, eye shadow, moisturizer, nail polish, liquid soap, and hair spray.

Unwanted plasticizers (often phthalates) can become contaminants in other polymers or products.. Other esters used in the industry include DINCH, Benzyl glycoates, and glycol benzoates, “Citroflex” and Eastman 168, although phthalates are widely perceived to have profoundly negative effects on health. 

Examples of projects we routinely execute involving phthalates include:

    •  Identification and quantitation of Phthalates in polymeric materials
    • Quantitation of phthalate contaminants from packaging
    • Investigation of Phthalates leachables from drug product container closure system (CCS)
    • Characterization of drug product for phthalate leachables

    Impact Analytical has polymer- and phthalate-specific methods developed for determining trace level contaminants.

    Phthalates we have experience with include:

      • diethylhexyl Phthalate (DEHP), CAS No 117-81-7
      • dioctyl Phthalate (DOP), CAS No 117-81-7
      • diisooctyl Phthalate (DIOP) CAS No 27554-26-3
      • di-n-butyl phthalate (DBP),CAS No 84-74-2
      • butyl benzyl phthalate (BBP), CAS No 85-68-7
      • diisononyl phthalate (DINP), CAS No 28553-12-0
      • diisodecyl phthalate (DIDP), CAS No 26761-40-0
      • di-n-octyl phthalate (DNOP), CAS No 117-84-0

      Impact Analytical has the latest generation GC and LC technology to enable us to reach the lowest levels of detection, contact the team today to learn more.

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