{"id":6171,"date":"2022-07-25T17:48:40","date_gmt":"2022-07-25T17:48:40","guid":{"rendered":"https:\/\/www.impactanalytical.com\/?page_id=6171"},"modified":"2022-08-25T16:32:56","modified_gmt":"2022-08-25T16:32:56","slug":"high-resolution-mass-spectrometry","status":"publish","type":"page","link":"https:\/\/www.impactanalytical.com\/high-resolution-mass-spectrometry\/","title":{"rendered":"High Resolution Mass Spectrometry"},"content":{"rendered":"

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Services<\/span><\/h6>\n

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High Resolution GC Mass Spectrometry<\/h1>\n

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High Resolution Mass Spectrometry Gas Chromatography<\/h2>\n

For regulated test materials reaching the detection limits required in such markets as the Pharmaceutical, Medical Device and AgroSciences requires the latest generation of GC technology.\u00a0 Impact Analytical has brought on board the latest edition Shimadzu Nexis GC-2030 coupled with a TQ8050 NX MS\/MS Detector and an HS-20 headspace analyzer. This new hardware provides quantitative GC-MS\/MS analyses of ultra-trace amounts, down to the femtogram level. What are some common areas where this technology is useful?<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Why Us” _builder_version=”4.16″ background_color=”#009dd5″ locked=”off” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.17.3″ hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”post_content” sticky_enabled=”0″][et_pb_column type=”1_2″ _builder_version=”4.17.3″ background_image=”https:\/\/www.impactanalytical.com\/wp-content\/uploads\/2022\/06\/21-IMP-1207-IMPACT-WEBSITE-SHOOT-61-scaled.jpg” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”post_content” title_text=”21-IMP-1207-IMPACT WEBSITE SHOOT-61″ sticky_enabled=”0″][et_pb_divider show_divider=”off” _builder_version=”4.17.3″ _module_preset=”default” custom_padding=”150px||150px||true|false” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”post_content” sticky_enabled=”0″][\/et_pb_divider][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_divider color=”#FFFFFF” divider_weight=”8px” _builder_version=”4.16″ max_width=”40px” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_divider][et_pb_text _builder_version=”4.17.3″ text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”16px” text_line_height=”2em” header_font=”Rubik|500|||||||” header_text_color=”#1a3066″ header_font_size=”54px” header_line_height=”1.3em” header_2_font=”|600|||||||” header_2_text_color=”#FFFFFF” header_2_font_size=”38px” header_2_line_height=”1.3em” hover_enabled=”0″ text_font_size_tablet=”” text_font_size_phone=”14px” text_font_size_last_edited=”on|phone” header_font_size_tablet=”44px” header_font_size_phone=”34px” header_font_size_last_edited=”on|phone” header_2_font_size_tablet=”30px” header_2_font_size_phone=”24px” header_2_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}” theme_builder_area=”post_content” sticky_enabled=”0″]<\/p>\n

Bioanalytical Services<\/h2>\n

The most common biological samples tested by GC-MS\/MS are plasma or serum for\u00a0pharmacokinetics, drug clearance, half- life, and bioavailability. \u00a0Urine samples may be tested to better understand biological elimination of the compound of interest.\u00a0<\/p>\n

Agrosciences<\/h2>\n

The GC-MS\/MS is used in the Agrosciences space for targeted (MRM mode) and non-targeted (scan mode) studies of small molecules. \u00a0The MRM mode affords ppt levels of sensitivity for most \u00a0pesticides, herbicides, and insecticides.\u00a0<\/p>\n

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Pharmaceuticals<\/h2>\n

The GC-MS\/MS can be used to determine many impurities and degradation products across various platforms. In addition to achieving very low levels of Volatile Organic Compounds (VOCs) a new pharmaceutical concern has recently emerged. N-nitroso dimethylamine (NDMA) \u00a0and other nitrosamines are \u00a0impurities found in some prescription medications. These compounds have been identified by the FDA as materials of concern and need to be tested for.\u00a0 One method for analyzing for these compounds is made using HR-GC\/MS according to the\u00a0FDA website<\/a>.<\/strong><\/span><\/p>\n

 <\/p>\n

Medical Devices<\/h2>\n
\n

Extractable and leachable studies look for trace amounts of substances which may come out of a specific project. GC-MS\/MS is a technique to allow extremely low detection and quantitation of potentially harmful materials.<\/p>\n<\/div>\n

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Give us a call and speak with an actual scientist.<\/span><\/p>\n

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ServicesHigh Resolution GC Mass SpectrometryHigh Resolution Mass Spectrometry Gas Chromatography For regulated test materials reaching the detection limits required in such markets as the Pharmaceutical, Medical Device and AgroSciences requires the latest generation of GC technology.\u00a0 Impact Analytical has brought on board the latest edition Shimadzu Nexis GC-2030 coupled with a TQ8050 NX MS\/MS Detector […]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"_links":{"self":[{"href":"https:\/\/www.impactanalytical.com\/wp-json\/wp\/v2\/pages\/6171"}],"collection":[{"href":"https:\/\/www.impactanalytical.com\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.impactanalytical.com\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.impactanalytical.com\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.impactanalytical.com\/wp-json\/wp\/v2\/comments?post=6171"}],"version-history":[{"count":3,"href":"https:\/\/www.impactanalytical.com\/wp-json\/wp\/v2\/pages\/6171\/revisions"}],"predecessor-version":[{"id":6177,"href":"https:\/\/www.impactanalytical.com\/wp-json\/wp\/v2\/pages\/6171\/revisions\/6177"}],"wp:attachment":[{"href":"https:\/\/www.impactanalytical.com\/wp-json\/wp\/v2\/media?parent=6171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}