{"id":4922,"date":"2022-05-18T20:39:34","date_gmt":"2022-05-18T20:39:34","guid":{"rendered":"https:\/\/www.impactanalytical.com\/?page_id=4922"},"modified":"2022-12-14T21:47:17","modified_gmt":"2022-12-14T21:47:17","slug":"sec-gpc-analysis","status":"publish","type":"page","link":"https:\/\/www.impactanalytical.com\/sec-gpc-analysis\/","title":{"rendered":"SEC\/GPC Analysis"},"content":{"rendered":"

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-Techniques-<\/span><\/h6>\n

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SEC\/GPC Analysis<\/strong><\/h1>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ custom_padding_last_edited=”on|tablet” admin_label=”About” _builder_version=”4.16″ background_image=”https:\/\/www.impactanalytical.com\/wp-content\/uploads\/2021\/10\/molecules-bg.png” background_size=”initial” background_position=”top_right” custom_padding=”||||false|false” custom_padding_tablet=”||||false|false” custom_padding_phone=”” locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” custom_padding_last_edited=”on|phone” _builder_version=”4.17.3″ custom_margin_tablet=”” custom_margin_phone=”” custom_margin_last_edited=”on|phone” custom_padding_tablet=”” custom_padding_phone=”||0px||false|false” global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.17.3″ background_image=”https:\/\/www.impactanalytical.com\/wp-content\/uploads\/2022\/07\/19-IMP-0619-ASSET-LOCKER-2-83-scaled.jpg” global_colors_info=”{}”][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_divider color=”#a6d5f3″ divider_weight=”8px” _builder_version=”4.16″ max_width=”40px” module_alignment=”left” locked=”off” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.18.0″ text_font=”||||||||” text_font_size=”16px” text_line_height=”2em” header_font=”Rubik|500|||||||” header_text_color=”#1a3066″ header_font_size=”54px” header_line_height=”1.3em” header_2_font=”|700|||||||” header_2_text_color=”#1E1E1E” header_2_font_size=”38px” header_2_line_height=”1.3em” text_font_size_tablet=”” text_font_size_phone=”14px” text_font_size_last_edited=”on|phone” header_font_size_tablet=”44px” header_font_size_phone=”34px” header_font_size_last_edited=”on|phone” header_2_font_size_tablet=”30px” header_2_font_size_phone=”24px” header_2_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

Background<\/h2>\n

Gel Permeation Chromatography (GPC),\u00a0also referred to as Size Exclusion Chromatography (SEC), is a valuable tool for the characterization of molecular weight, average molecular weight,\u00a0and molecular weight distribution for polymers. It is often necessary to separate polymers, both to analyze them as well as to purify the desired product. When characterizing polymers, it is important to consider the polydispersity index (PDI), as well as the molecular weight. Polymers can be characterized by a variety of definitions for molecular weight, including the number average molecular weight (Mn), the weight average molecular weight (Mw) (see molar mass distribution),\u00a0and\u00a0the size average molecular weight (Mz).\u00a0GPC allows for the determination of PDI as well as\u00a0Mn, Mw, and Mz.<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ admin_label=”Why Us” _builder_version=”4.16″ background_color=”#009dd5″ locked=”off” global_colors_info=”{}”][et_pb_row column_structure=”1_2,1_2″ make_equal=”on” _builder_version=”4.17.3″ global_colors_info=”{}”][et_pb_column type=”1_2″ _builder_version=”4.17.3″ background_image=”https:\/\/www.impactanalytical.com\/wp-content\/uploads\/2022\/07\/19-IMP-0619-ASSET-LOCKER-2-87-scaled.jpg” global_colors_info=”{}”][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ global_colors_info=”{}”][et_pb_divider color=”#FFFFFF” divider_weight=”8px” _builder_version=”4.16″ max_width=”40px” global_colors_info=”{}”][\/et_pb_divider][et_pb_text _builder_version=”4.18.0″ text_font=”||||||||” text_text_color=”#FFFFFF” text_font_size=”16px” text_line_height=”2em” header_font=”Rubik|500|||||||” header_text_color=”#1a3066″ header_font_size=”54px” header_line_height=”1.3em” header_2_font=”|600|||||||” header_2_text_color=”#FFFFFF” header_2_font_size=”38px” header_2_line_height=”1.3em” text_font_size_tablet=”” text_font_size_phone=”14px” text_font_size_last_edited=”on|phone” header_font_size_tablet=”44px” header_font_size_phone=”34px” header_font_size_last_edited=”on|phone” header_2_font_size_tablet=”30px” header_2_font_size_phone=”24px” header_2_font_size_last_edited=”on|phone” locked=”off” global_colors_info=”{}”]<\/p>\n

Background<\/h2>\n

Impact Analytical has extensive expertise and instrument capability in this area. We can characterize polymers from all classes,\u00a0using solvent systems from tetrahydrofuran (THF),\u00a0to hexafluroisopropanol (HFIP),\u00a0to aqueous. We offer both differential refractive index (DRI) and multi-angle laser light scattering (MALLS) detection. Standard calibration is used to give relative molecular weight with DRI analysis, while MALLS detection gives \u201ctrue\u201d molecular weight. Please note that we cannot analyze CPDS with high temp requirements. Impact Analytical perform all testing to GLP standards and ISO 9001:2015.<\/p>\n

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Examples of polymer systems characterized include:<\/h2>\n
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