Tablet Dissolution Testing
Evaluation of Bioavailability
One of the most important factors to understand during drug development is the dosage form’s “bioavailability”. This refers to the rate at which the drug product becomes available for absorption by the body. The rate is governed by the time required for the drug product to dissolve in the gastrointestinal tract, and release the drug product contained in the tablet or capsule.
Dissolution testing allows bioavailability to be measured, which is done using a tablet dissolution apparatus. This system simulates the environment of the human gastrointestinal tract. Samples are taken periodically through the study and assayed to measure drug product concentration. A plot of the concentration over time of the study can be created that shows the rate of release of the drug substance from the dosage form.
Impact Analytical has teamed the latest tablet dissolution apparatus with our industry leading analytical technologies to provide tablet dissolution testing services for all types of drug product and dosage forms.
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