Case Study: Elemental Analysis to Identify Contaminant in Brine SolutionsImpurity Analysis
Impurity Identification in Finished Products, Intermediates and Raw Materials
Impact Analytical is a leading provider of impurity identification services to the pharmaceutical, plastics, consumer products, medical device, packaging, and specialty chemical industries. Having solved hundreds of impurity problems, there isn’t much that we haven’t analyzed or characterized in our laboratories. Impurities or unknown components can cause irreparable damage to a product even at trace levels, resulting in poor consumer satisfaction. Impurities in a finished product can cause even worse situations; an issue involving product safety.
At Impact Analytical, we have a full breadth of analytical capabilities to handle impurity analysis problems ranging from identification of complete unknowns to quantitation of well characterized unknowns. Examples of unknown impurity problems we have recently solved include:
- Impurity Testing in Product Batches by GC-MS analysis
- Impurity Identification in Cosmetic Materials by FT-IR
- Quantitation of Residual BPA In Food Packaging Materials
- Quantitation of Diethylene Glycol in Toothpaste
- Quantitation of Melamine in Dog Food
- Lead Determination in Toys
- Color Body Determination in TPO Materials
- Impurity analysis of Unknown Impurity in Chemical Production Process
Common instrumentation Impact Analytical utilizes to separate, identify and ultimately solve unknown impurity issues include:
- Gas Chromatography Mass Spectrometry (GC-MS)
- Chemical Ionization Mass Spectrometry (CI-MS)
- Fourier Transform Infrared Spectroscopy (FT-IR)
- Liquid Chromatography Mass Spectrometry (LC-MS)
- Scanning Electron Microscopy - Energy Dispersive Spectroscopy (SEM/EDS)
- Proton Induced X-ray Emission (PIXE)
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