Gel Permeation Chromatography
Gel permeation chromatography (GPC), also referred to as size exclusion chromatography (SEC), is a valuable tool for the characterization of molecular weight, average molecular weight and molecular weight distribution for polymers. Impact Analytical has extensive expertise and instrument capability in this area. We can characterize polymers from all classes using solvent systems from tetrahydrofuran (THF) to hexafluroisopropanol (HFIP). We offer both differential refractive index (DRI) and multi-angle laser light scattering (MALLS) detection. Standard calibration is used to give relative molecular weight with DRI analysis, while MALLS detection gives “true” molecular weight.
Examples of polymer systems characterized include: